Fabrizio Pertusati, PhD
Fabrizio holds a MSc in Physical Organic Chemistry from Turin University (synthesis and characterisation of cationic surfactants) and a PhD in asymmetric organic chemistry from the Cardiff School of Chemistry, (atropisomeric bis-quinazolinones).
He conducted his post-doctoral training at Emory University (solid-phase synthesis of polymethine dyes) and in the laboratory of the Nobel laureate Prof. George Olah, at the University of Southern California, where he gained expertise in organofluorine, organoboron and polymer chemistry).
Since 2011, he as been working in Chris McGuigan’s group where he was involved in various drug discovery projects.
Research in his group involve the design and synthesis of small molecules as therapeutics against Rare diseases (congenital disorder of glycosylation, Mitochondrial depletion syndrome, Niemann-Pick), infectious diseases, and recently antimicrobial drug discovery
Key Expertises
Organofluorine, organophosphorus, carbohydrates chemistry.
Design and synthesis of phosphate/phosphonate prodrugs of carbohydrate scaffolds
Translational drug Discovery
Rare diseases drug discovery: GNE myopathy, Cystinosis and Niemann-Pick releated disorders.
Synthesis of small molecules with antibiotic activities